Baku, November 26, Sevda Jafarova, AZERTAC
Research conducted in 2025 at academician Ali Guliyev Institute of Chemistry of Additives of the Ministry of Science and Education achieved significant results in addressing the problem of “Specific synthesis of highly effective physiologically active compounds, including pharmaceuticals, various organic reagents, and composite materials, using fine organic synthesis and computer modeling, as well as studying the mechanism of functional action.”
Kamala Mammadova, Senior Researcher at the Institute of Chemistry of Additives Public Relations Department, stated this in an interview with AZERTAC.
Kamala Mammadova noted that these developments are primarily related to the production of the highly alkaline multifunctional additive AKI-152 for motor oils, additives that effectively improve the tribological properties of lubricants, new Schiff bases for high-tech functional materials, and graphite lubricants that meet environmental requirements. These also include the development of dual inhibitors of certain enzymes and their isoforms. Molecular docking and pharmacophoric modeling studies are also ongoing to explore the mechanism of glycyrrhizin’s interaction as a potential therapeutic agent against COVID-19. Research is also underway in the computational chemistry of new heterocyclic compounds with potential bactericidal properties, as well as the production and detailed study of biologically active pharmaceuticals.
She emphasized that results of practical significance include the development of a new additive that effectively improves the antiwear and extreme pressure properties of motor oils and lubricants for high-performance diesel engines in modern ground vehicles.
The results of fundamental and applied scientific research are reflected in three books and monographs, 36 scientific articles published in reputable journals (25 of which were published internationally), and 16 patents.