Traditional herbal remedies are widely used as complementary treatments for viral infections. Given this, a joint study by scientists from Baku State University and the Institute of Chemistry of Additives conducted a detailed study of the compound glycyrrhizin, found in licorice root. Based on the results, this compound was proposed as a potential therapeutic agent for the treatment of COVID-19.
The report states that molecular docking modeling was used in the study. A domain-specific docking approach was used for all calculations. Molecular docking studies of glycyrrhizin showed that this compound forms a stable complex with SARS-CoV-2 target proteins. Based on the results, pharmacophoric models of glycyrrhizin binding to the identified receptors were proposed.
The results indicate that glycyrrhizin is a promising antiviral candidate and warrants further research for the treatment of COVID-19.
The results of our scientists’ international research are published as articles in the journal Biomaterials Translational, which has an impact factor of 9.8 and a Q1 classification and is indexed in the Scopus database (https://www.biomat-trans.com/journal/BMT/articles/online_first/220).
